156052-68-5
Chemical Structure
Zoxamide
Synonym(s): RH-7281
- CAS No.: 156052-68-5
- Formula:C14H16Cl3NO2
- Molecular Weight:336.64
IUPAC Name: 3,5-dichloro-N-(1-chloro-3-methyl-2-oxopentan-3-yl)-4-methylbenzamide
InChIKey: SOUGWDPPRBKJEX-UHFFFAOYSA-N
SMILES: O=C(NC(C)(CC)C(CCl)=O)C1=CC(Cl)=C(C)C(Cl)=C1
Biological Activity: Zoxamide (RH-7281) is an oomycete Fungicide and covalent β-tubulin inhibitor. RH-7281 inhibits the assembly of tubulin into microtubules in vitro. Zoxamide binds covalently to β-tubulin, disrupting microtubule assembly and the cytoskeleton. Zoxamide blocks nuclear division in germinated hyphae of Phytophthora capsici and inhibits hyphal growth of Phytophthora capsici[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Zoxamide | 99.05% | Zoxamide (RH-7281) is an oomycete Fungicide and covalent β-tubulin inhibitor. RH-7281 inhibits the assembly of tubulin into microtubules in vitro. Zoxamide binds covalently to β-tubulin, disrupting microtubule assembly and the cytoskeleton. Zoxamide blocks nuclear division in germinated hyphae of Phytophthora capsici and inhibits hyphal growth of Phytophthora capsici. | ||||||||||||||||||||
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Zoxamide (Standard) | ≥98% | Zoxamide (Standard) is the analytical standard of Zoxamide. This product is intended for research and analytical applications. Zoxamide (RH-7281) is an oomycete fungicide. Zoxamide arrests nuclear division in Phytophthora capsici germlings and destroyed the microtubule cytoskeleton. | ||||||||||||||||||||
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References
- [1]. Mei X, et al. Proteomic analysis on zoxamide-induced sensitivity changes in Phytophthora cactorum. Pestic Biochem Physiol. 2015;123:9-18. [Content Brief]
- [2]. Young D H, et al. Mode of action of zoxamide (RH-7281), a new Oomycete fungicide[J]. Pesticide Biochemistry and Physiology, 2001, 69(2): 100-111.
