1565828-01-4
1565828-01-4
Chemical Structure
BRD8518
- CAS No.: 1565828-01-4
- Formula:C33H32F3N3O5
- Molecular Weight:607.62
InChIKey: CCWJWXJNOLFYBD-RWPDHJIBSA-N
SMILES: O=C(NC1=CC=C2C(C(N(C)[C@H]3CC[C@@H](CC(NC4CC(C=CC=C5)=C5C4)=O)O[C@H]3CO2)=O)=C1)C6=CC=C(C(F)(F)F)C=C6
Biological Activity: BRD8518 is a PCSK9 inhibitor (EC50=0.23 μM). BRD8518 lowers blood lipids by upregulating LDLR expression and stimulating LDL uptake. BRD8518 can be used in the study of cardiovascular diseases[1].
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BRD8518 | BRD8518 is a PCSK9 inhibitor (EC50=0.23 μM). BRD8518 lowers blood lipids by upregulating LDLR expression and stimulating LDL uptake. BRD8518 can be used in the study of cardiovascular diseases. | |||||||||||||||||||||
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