15663-27-1
15663-27-1
Chemical Structure
Cisplatin
Synonym(s): cis-Platinum; CDDP; cis-Diaminodichloroplatinum
- CAS No.: 15663-27-1
- Formula:Pt(NH3)2Cl2
- Molecular Weight:300.05
InChIKey: LXZZYRPGZAFOLE-UHFFFAOYSA-L
SMILES: Cl[Pt](Cl)([NH3])[NH3]
Biological Activity: Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cisplatin | 99.30% | Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy. | ||||||||||||||||||||
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References
- [1]. Wang X, et al. Requirement for ERK activation in cisplatin-induced apoptosis. J Biol Chem. 2000 Dec 15;275(50):39435-43. [Content Brief]
- [2]. Cummings BS, et al. Cisplatin-induced renal cell apoptosis: caspase 3-dependent and -independent pathways. J Pharmacol Exp Ther. 2002 Jul;302(1):8-17. [Content Brief]
- [3]. Park HR, et al. Enhanced antitumor efficacy of cisplatin in combination with HemoHIM in tumor-bearing mice. BMC Cancer. 2009 Mar 17;9:85. [Content Brief]
