156635-05-1
156635-05-1
Chemical Structure
BIBB 515
- CAS No.: 156635-05-1
- Formula:C22H21ClN2O2
- Molecular Weight:380.87
IUPAC Name: (4-chlorophenyl)(4-(4-(4,5-dihydrooxazol-2-yl)benzylidene)piperidin-1-yl)methanone
InChIKey: JQNWPWUJMRAASQ-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C=C1)Cl)N2CC/C(CC2)=C\C3=CC=C(C=C3)C4=NCCO4
Biological Activity: BIBB 515 is a potent, selective and orally active 2,3-oxidosqualene cyclase (OSC) inhibitor with ED50 values of 0.2-0.5 mg/kg and 0.36-33.3 mg/kg in rats and mice (1-5 hours), respectively. BIBB 515 exerts lipid-lowering effect mainly by inhibiting the production of low-density lipoprotein (LDL)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BIBB 515 | 99.56% | BIBB 515 is a potent, selective and orally active 2,3-oxidosqualene cyclase (OSC) inhibitor with ED50 values of 0.2-0.5 mg/kg and 0.36-33.3 mg/kg in rats and mice (1-5 hours), respectively. BIBB 515 exerts lipid-lowering effect mainly by inhibiting the production of low-density lipoprotein (LDL). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
