157000-65-2
157000-65-2
Chemical Structure
Uvaol diacetate
- CAS No.: 157000-65-2
- Formula:C34H54O4
- Molecular Weight:526.79
InChIKey: BAZMEWBREGUVCK-QCNIQUMGSA-N
SMILES: CC(OC[C@]12[C@]([C@H]([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@]4(C)[C@@](C(C)([C@H](CC4)OC(C)=O)C)([H])CC5)([H])[C@]5(C)[C@]3(C)CC1)=O
Biological Activity: Uvaol diacetate (Compound 5) is a triterpenoid derived from the leaves of Nerium oleunder L. and is an analog of Uvaol (HY-N1109). Uvaol has protective effects against DNA damage and can also induce apoptosis in cancer cells[1][2].
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Uvaol diacetate | Uvaol diacetate (Compound 5) is a triterpenoid derived from the leaves of Nerium oleunder L. and is an analog of Uvaol (HY-N1109). Uvaol has protective effects against DNA damage and can also induce apoptosis in cancer cells. | |||||||||||||||||||||
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References
- [1]. Martín R, et al. Natural triterpenic diols promote apoptosis in astrocytoma cells through ROS-mediated mitochondrial depolarization and JNK activation. PLoS One. 2009 Jun 22;4(6):e5975. [Content Brief]
- [2]. Siddiqui, et al. Kaneric Acid, a New Triterpene from the Leaves of Nerium oleander. Journal of Natural Products. 1986; 49(6):1086–1090.
