157047-96-6
157047-96-6
Chemical Structure
Benzomalvin A
Synonym(s): (-)-Benzomalvin A
- CAS No.: 157047-96-6
- Formula:C24H19N3O2
- Molecular Weight:381.43
IUPAC Name: 7-benzyl-6-methyl-6,7-dihydrobenzo[6,7][1,4]diazepino[2,1-b]quinazoline-5,13-dione
InChIKey: YYWUABJYAOCACI-UHFFFAOYSA-N
SMILES: O=C1N(C)[C@@H](CC2=CC=CC=C2)C(N3C4=CC=CC=C14)=NC5=C(C=CC=C5)C3=O
Biological Activity: Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively[1].
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Benzomalvin A | Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively. | |||||||||||||||||||||
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