158932-33-3
Chemical Structure
(R,R)-Secoisolariciresinol diglucoside
Synonym(s): (R,R)-SDG; (R,R)-LGM2605
- CAS No.: 158932-33-3
- Formula:C32H46O16
- Molecular Weight:686.70
IUPAC Name: (2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-6,6'-(((2R,3R)-2,3-bis(4-hydroxy-3-methoxybenzyl)butane-1,4-diyl)bis(oxy))bis(2-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol)
InChIKey: SBVBJPHMDABKJV-PGCJWIIOSA-N
SMILES: COC(C=C1C[C@@H](CO[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)[C@H](CO[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)CC4=CC(OC)=C(C=C4)O)=C(C=C1)O
Biological Activity: (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is an isomer of Secoisolariciresinol diglucoside (HY-105008). (R,R)-Secoisolariciresinol diglucoside scavenges hydroxyl radicals, peroxyl radicals, and DPPH radicals. (R,R)-Secoisolariciresinol diglucoside reduces γ-ray-induced strand breaks in calf thymus DNA. (R,R)-Secoisolariciresinol diglucoside can be used in studies of oxidant-dependent inflammatory tissue injury[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(R,R)-Secoisolariciresinol diglucoside | 99.21% | (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is an isomer of Secoisolariciresinol diglucoside (HY-105008). (R,R)-Secoisolariciresinol diglucoside scavenges hydroxyl radicals, peroxyl radicals, and DPPH radicals. (R,R)-Secoisolariciresinol diglucoside reduces γ-ray-induced strand breaks in calf thymus DNA. (R,R)-Secoisolariciresinol diglucoside can be used in studies of oxidant-dependent inflammatory tissue injury. | ||||||||||||||||||||
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(R,R)-Secoisolariciresinol diglucoside (Standard) | ≥98% | (R,R)-Secoisolariciresinol diglucoside (Standard) is the analytical standard of (R,R)-Secoisolariciresinol diglucoside. This product is intended for research and analytical applications. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells. | ||||||||||||||||||||
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(R,R)-Secoisolariciresinol diglucoside-d6 | (R,R)-Secoisolariciresinol diglucoside-d6 is deuterated labeled (R,R)-Secoisolariciresinol diglucoside (HY-N6937). (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells. | |||||||||||||||||||||
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References
- [1]. Mishra OP, et al. Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits myeloperoxidase activity in inflammatory cells. Biochimica et biophysica acta. General subjects. 2018 Jun;1862(6):1364-1375. [Content Brief]
- [2]. Mishra OP, et al. Novel synthetic (S,S) and (R,R)-secoisolariciresinol diglucosides (SDGs) protect naked plasmid and genomic DNA From gamma radiation damage. Radiat Res. 2014 Jul;182(1):102-10. [Content Brief]
- [3]. Mishra OP, et al. Synthesis and antioxidant evaluation of (S,S)- and (R,R)-secoisolariciresinol diglucosides (SDGs). Bioorg Med Chem Lett. 2013 Oct 1;23(19):5325-8. [Content Brief]
