159359-94-1
Chemical Structure
AGN 191976
- CAS No.: 159359-94-1
- Formula:C21H32O6
- Molecular Weight:380.48
IUPAC Name: (Z)-7-((1R,5S,6R,7R)-7-((S,E)-3-hydroxyoct-1-en-1-yl)-3-oxo-2,4-dioxabicyclo[3.2.1]octan-6-yl)hept-5-enoic acid
InChIKey: VKJGCWRFKHGFHT-YNNPMVKQSA-N
SMILES: O=C(CCC/C=C\C[C@H]1[C@]2(OC(O[C@@]([H])([C@@H]1/C=C/[C@H](CCCCC)O)C2)=O)[H])O
Biological Activity: AGN 191976 is a potent and selective thromboxane A2-sensitive (TP) receptor agonist with EC50 values of 0.23 nM and 24 nM in rat aorta and human platelets, respectively. AGN 191976 has potent IOP-lowering effects in dogs and monkeys. AGN 191976 can be used to study vascular biology and the role of thromboxane A2 in vascular function[1].
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AGN 191976 | AGN 191976 is a potent and selective thromboxane A2-sensitive (TP) receptor agonist with EC50 values of 0.23 nM and 24 nM in rat aorta and human platelets, respectively. AGN 191976 has potent IOP-lowering effects in dogs and monkeys. AGN 191976 can be used to study vascular biology and the role of thromboxane A2 in vascular function. | |||||||||||||||||||||
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