15956-28-2
15956-28-2
Chemical Structure
Dirhodium tetraacetate
Synonym(s): Tetrakis(acetato)dirhodium(II); Rhodium(II) acetate dimer
- CAS No.: 15956-28-2
- Formula:Rh2(OOCCH3)4
- Molecular Weight:441.99
InChIKey: SYBXSZMNKDOUCA-UHFFFAOYSA-J
SMILES: O1=C([O-][Rh+2]234O=C([O-][Rh+2]14(O=C([O-]2)C)[O-]C(=O3)C)C)C
Biological Activity: Dirhodium tetraacetate (Tetrakis (acetato) dirhodium (II)) is an anticancer agent. Dirhodium tetraacetate functionally inhibits the activities of DNA polymerase I and RNA polymerase. It also acts as a catalyst and can be used to construct rhodium-based artificial metalloenzymes[1][2].
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Dirhodium tetraacetate | 98.3% | Dirhodium tetraacetate (Tetrakis (acetato) dirhodium (II)) is an anticancer agent. Dirhodium tetraacetate functionally inhibits the activities of DNA polymerase I and RNA polymerase. It also acts as a catalyst and can be used to construct rhodium-based artificial metalloenzymes. | ||||||||||||||||||||
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References
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[1]. Wong DL, et al. Glutathione binding to dirhodium tetraacetate: a spectroscopic, mass spectral and computational study of an anti-tumour compound. Metallomics. 2017 May 24;9(5):501-516.
[Content Brief] - [2]. Tito G, et al. Dirhodium Tetraacetate Binding to Lysozyme at Body Temperature. Int J Mol Sci. 2025;26(14):6582. Published 2025 Jul 9. [Content Brief]
