1603-47-0
1603-47-0
Chemical Structure
8-Hydroxybergapten
- CAS No.: 1603-47-0
- Formula:C12H8O5
- Molecular Weight:232.19
IUPAC Name: 9-hydroxy-4-methoxy-7H-furo[3,2-g]chromen-7-one
InChIKey: MVJHUMZXIJPVHV-UHFFFAOYSA-N
SMILES: COC1=C(C=CO2)C2=C(O)C(O3)=C1C=CC3=O
Biological Activity: 8-hydroxybergapten is O-methylated by cell-free extracts of Ruta cells to isopimpinellin, in reactions mediated by discrete O-methyltransferases. 8-hydroxybergapten has excellent anti-wrinkle effect[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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8-Hydroxybergapten | 99.87% | 8-hydroxybergapten is O-methylated by cell-free extracts of Ruta cells to isopimpinellin, in reactions mediated by discrete O-methyltransferases. 8-hydroxybergapten has excellent anti-wrinkle effect. | ||||||||||||||||||||
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5-Hydroxy-8-methoxypsoralen | 99.82% | 5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite of Xanthotoxin. Xanthotoxin is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight. | ||||||||||||||||||||
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Methoxsalen | 99.97% | Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor. | ||||||||||||||||||||
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Bergapten | 99.85% | Bergapten is a natural anti-inflammatory and anti-tumor agent. Bergapten is inhibitory towards mouse and human CYP isoforms. | ||||||||||||||||||||
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Pimpinellin | 99.67% | Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis. | ||||||||||||||||||||
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Isobergapten (Standard) | ≥98% | Isobergapten (Standard) is the analytical standard of Isobergapten. This product is intended for research and analytical applications. Isobergapten is an allelopathic inhibitor isolated from seeds of Hevacleum laciniatum. | ||||||||||||||||||||
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Isopimpinellin (Standard) | ≥98% | Isopimpinellin (Standard) is the analytical standard of Isopimpinellin. This product is intended for research and analytical applications. Isopimpinellin, an orally active compound isolated from Glomerella cingulata. Isopimpinellin blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene. Isopimpinellin possesses anti-leishmania effect. | ||||||||||||||||||||
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Phellopterin (Standard) | ≥98% | Phellopterin (Standard) is the analytical standard of Phellopterin. Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus. | ||||||||||||||||||||
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Cnidilin | 99.0% | Cnidilin (Knidilin) is isolated from the root of Angelica dahurica. | ||||||||||||||||||||
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Sphondin | 99.70% | Sphondin possesses an inhibitory effect on IL-1β-induced increase in the level of COX-2 protein and PGE2 release in A549 cells. | ||||||||||||||||||||
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5,8-Dihydroxypsoralen | 5,8-Dihydroxypsoralen is a natural product. | |||||||||||||||||||||
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