1603833-55-1
1603833-55-1
Chemical Structure
Amyloid-β-IN-2
- CAS No.: 1603833-55-1
- Formula:C22H21F2N3O2
- Molecular Weight:397.42
InChIKey: KNDVEZJMPNKCSL-HNNXBMFYSA-N
SMILES: FC1=CC(F)=CC(NC(C2=CC3=CC([C@@H]4CN(CCC4)C(C)=O)=CC=C3N2)=O)=C1
Biological Activity: Amyloid-β-IN-2 (Compound EX.112) is a selective γ-secretase inhibitor. Amyloid-β-IN-2 inhibits Aβ42 secretion in H4 cells with an EC50 value of 226 nM. Amyloid-β-IN-2 is promising for research of Alzheimer's disease (AD) and other diseases related to Aβ deposition[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Amyloid-β-IN-2 | 99.47% | Amyloid-β-IN-2 (Compound EX.112) is a selective γ-secretase inhibitor. Amyloid-β-IN-2 inhibits Aβ42 secretion in H4 cells with an EC50 value of 226 nM. Amyloid-β-IN-2 is promising for research of Alzheimer's disease (AD) and other diseases related to Aβ deposition. | ||||||||||||||||||||
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