1604838-69-8
1604838-69-8
Chemical Structure
NFC nitro probe 1
- CAS No.: 1604838-69-8
- Formula:C19H19NO6
- Molecular Weight:357.36
InChIKey: YJVXNTQPXSFATO-UHFFFAOYSA-N
SMILES: CC1(C)OC2=C3C(OC(C=C3CCC)=O)=C4C(OC([N+]([O-])=O)=C4)=C2CC1
Biological Activity: NFC nitro probe 1 (compound 18) is an NFC termed probe for Mtb detection. NFC nitro probe 1 (compound 18) shows high potency for R-Mtb and NR-Mtb[1][2].
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NFC nitro probe 1 | NFC nitro probe 1 (compound 18) is an NFC termed probe for Mtb detection. NFC nitro probe 1 (compound 18) shows high potency for R-Mtb and NR-Mtb. | |||||||||||||||||||||
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References
- [1]. Ana Negri, et al. Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis. ACS Infect Dis. 2018 May 11;4(5):771-787. [Content Brief]
- [2]. Purong Zheng, et al. Synthetic calanolides with bactericidal activity against replicating and nonreplicating Mycobacterium tuberculosis. J Med Chem. 2014 May 8;57(9):3755-72. [Content Brief]
