1609067-49-3
Chemical Structure
TrkB agonist-1
- CAS No.: 1609067-49-3
- Formula:C19H16N2O6
- Molecular Weight:368.34
IUPAC Name: 4-oxo-2-phenyl-4H-chromene-7,8-diyl bis(methylcarbamate)
InChIKey: NWWRHMSYZTWUBD-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=CC=CC=C2)OC3=C(OC(NC)=O)C(OC(NC)=O)=CC=C13
Biological Activity: TrkB agonist-1 is an orally active, blood-brain barrier-permeable TrkB agonist. TrkB agonist-1 activates the TrkB signaling pathway and its downstream AKT and ERK/MAPK pathways via its released parent compound, reduces AEP enzyme activity and inhibits its activation, and simultaneously suppresses the production of pro-inflammatory cytokines. TrkB agonist-1 is used in the research of Alzheimer's disease[1].
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TrkB agonist-1 | 99.2% | TrkB agonist-1 is an orally active, blood-brain barrier-permeable TrkB agonist. TrkB agonist-1 activates the TrkB signaling pathway and its downstream AKT and ERK/MAPK pathways via its released parent compound, reduces AEP enzyme activity and inhibits its activation, and simultaneously suppresses the production of pro-inflammatory cytokines. TrkB agonist-1 is used in the research of Alzheimer's disease. | ||||||||||||||||||||
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