1609384-59-9
1609384-59-9
Chemical Structure
XIAP BIR2/BIR2-3 inhibitor-1
- CAS No.: 1609384-59-9
- Formula:C72H96N16O14
- Molecular Weight:1409.63
InChIKey: UZIAKDBFVNIMHM-AHKGGJCZSA-N
SMILES: O=C(N1[C@@](C(N[C@H](C(N[C@H](CCCN2C=C(CO[C@@](CCN3C([C@H](C(C)(C)C)NC([C@H](C)NC)=O)=O)([H])[C@@]3([H])C4=O)N=N2)C(O)=O)=O)CC5=CC(C=CC=C6)=C6C=C5)=O)([H])[C@@](OCC7=CN(CCC[C@@H](NC([C@@H](N4)CC8=CC(C=CC=C9)=C9C=C8)=O)C(O)=O)N=N7)([H])CC1)[C@H](C(C)(C)C)NC([C@H](C)NC)=O
Biological Activity: XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) is a dual inhibitor of BIR2 and BIR2-3 with IC50s of 1.9 and 0.8 nM, respectively. XIAP BIR2/BIR2-3 inhibitor-1 can used in study cancers[1].
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XIAP BIR2/BIR2-3 inhibitor-1 | XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) is a dual inhibitor of BIR2 and BIR2-3 with IC50s of 1.9 and 0.8 nM, respectively. XIAP BIR2/BIR2-3 inhibitor-1 can used in study cancers. | |||||||||||||||||||||
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