1609580-99-5
1609580-99-5
Chemical Structure
Noncatechol agonist-1
- CAS No.: 1609580-99-5
- Formula:C20H17N3O4
- Molecular Weight:363.37
IUPAC Name: 6-(4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl)-1,5-dimethylpyrimidine-2,4(1H,3H)-dione
InChIKey: CKMFOKUQUOYIOR-UHFFFAOYSA-N
SMILES: CC1=C(C2=C(C)C(NC(N2C)=O)=O)C=CC(OC3=C4C(OC=C4)=CC=N3)=C1
Biological Activity: Noncatechol agonist-1 (19) is a Noncatechol agonist with full efficacy at both D1R-G protein and D1R-β-arrestin2 pathways, with pEC50 values of 8.41 for D1R-mediated cAMP production and 7.7 for β-arrestin2 recruitment, respectively[1].
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Noncatechol agonist-1 | Noncatechol agonist-1 (19) is a Noncatechol agonist with full efficacy at both D1R-G protein and D1R-β-arrestin2 pathways, with pEC50 values of 8.41 for D1R-mediated cAMP production and 7.7 for β-arrestin2 recruitment, respectively. | |||||||||||||||||||||
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