1610516-67-0
1610516-67-0
Chemical Structure
ML318
- CAS No.: 1610516-67-0
- Formula:C14H8F4N2
- Molecular Weight:280.22
IUPAC Name: 2-(4-fluorophenyl)-2-(6-(trifluoromethyl)pyridin-2-yl)acetonitrile
InChIKey: DXQNDKQUHKVTTC-UHFFFAOYSA-N
SMILES: N#CC(C1=CC=C(F)C=C1)C2=NC(C(F)(F)F)=CC=C2
Biological Activity: ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ML318 | 99.26% | ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions. | ||||||||||||||||||||
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ML318 (Standard) | ≥98% | ML318 (Standard) is the analytical standard of ML318 (HY-129123). This product is intended for research and analytical applications. ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions. | ||||||||||||||||||||
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