1610537-25-1
1610537-25-1
Chemical Structure
Metallo-β-lactamase-IN-8
- CAS No.: 1610537-25-1
- Formula:C13H11ClN2O4S
- Molecular Weight:326.76
IUPAC Name: 4-((4-chlorophenyl)sulfonamido)-N-hydroxybenzamide
InChIKey: RPRDFXZWOJZMRF-UHFFFAOYSA-N
SMILES: O=C(NO)C1=CC=C(NS(=O)(C2=CC=C(Cl)C=C2)=O)C=C1
Biological Activity: Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity[1].
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Metallo-β-lactamase-IN-8 | Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity. | |||||||||||||||||||||
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