1613196-89-6
1613196-89-6
Chemical Structure
ATR-IN-27
- CAS No.: 1613196-89-6
- Formula:C22H25F2N9O2
- Molecular Weight:485.49
IUPAC Name: 2-amino-6-fluoro-N-(5-fluoro-4-(4-(piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
InChIKey: ICYWWCROPRXAKM-UHFFFAOYSA-N
SMILES: O=C(C1=C2N=CC(F)=CN2N=C1N)NC3=C(N4CCC(CC4)C(N5CCNCC5)=O)C(F)=CN=C3
Biological Activity: ATR-IN-27 (Compound I-G-12) is an ATR inhibitor with a Ki value greater than 0.01 μM but less than 1 μM. ATR-IN-27 sensitizes colorectal cancer cells to Cisplatin (HY-17394)[1].
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ATR-IN-27 | ATR-IN-27 (Compound I-G-12) is an ATR inhibitor with a Ki value greater than 0.01 μM but less than 1 μM. ATR-IN-27 sensitizes colorectal cancer cells to Cisplatin (HY-17394). | |||||||||||||||||||||
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