1614245-13-4
1614245-13-4
Chemical Structure
Schisanchinin D
- CAS No.: 1614245-13-4
- Formula:C23H30O6
- Molecular Weight:402.48
InChIKey: FYSHYFPJBONYCQ-OLZOCXBDSA-N
SMILES: OC1=C(OC)C(OC)=CC2=C1C3=C(OC)C(OC)=C(OC)C=C3C[C@H](C)[C@H](C)C2
Biological Activity: Schisanchinin D is an NO release inhibitor found in the fruits of Schisandra chinensis. Schisanchinin D can inhibit the release of nitric oxide (NO) by lipopolysaccharide (LPS)-activated microglia in primary murine BV2 microglia cells. Schisanchinin D is promising for research of neurodegenerative diseases such as Alzheimer's disease (AD)[1][2].
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Schisanchinin D | Schisanchinin D is an NO release inhibitor found in the fruits of Schisandra chinensis. Schisanchinin D can inhibit the release of nitric oxide (NO) by lipopolysaccharide (LPS)-activated microglia in primary murine BV2 microglia cells. Schisanchinin D is promising for research of neurodegenerative diseases such as Alzheimer's disease (AD). | |||||||||||||||||||||
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References
- [1]. Hu D, et al. Dibenzocyclooctadiene lignans from Schisandra chinensis and their inhibitory activity on NO production in lipopolysaccharide-activated microglia cells. Phytochemistry. 2014 Aug;104:72-8. [Content Brief]
- [2]. Jafernik K, et al. Comprehensive review of dibenzocyclooctadiene lignans from the Schisandra genus: anticancer potential, mechanistic insights and future prospects in oncology. Chin Med. 2024 Jan 24;19(1):17. [Content Brief]
