1621002-27-4
1621002-27-4
Chemical Structure
PF-06672131
- CAS No.: 1621002-27-4
- Formula:C23H21ClFN5O2
- Molecular Weight:453.90
SMILES: O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1OCC#C)/C=C/CN(C)C
Biological Activity: PF-06672131 is an alkynylated afatinib derivative and a small molecule probe that is reactive to cysteine. PF-06672131 is an inhibitor of epidermal growth factor receptor (EGFR) kinase that targets the ATP pockets of EGFR. PF-06672131 can be used for activity-based protein profiling studies[1].
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PF-06672131 | 99.47% | PF-06672131 is an alkynylated afatinib derivative and a small molecule probe that is reactive to cysteine. PF-06672131 is an inhibitor of epidermal growth factor receptor (EGFR) kinase that targets the ATP pockets of EGFR. PF-06672131 can be used for activity-based protein profiling studies. | ||||||||||||||||||||
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