162112-37-0
162112-37-0
Chemical Structure
RWJ 50271
- CAS No.: 162112-37-0
- Formula:C18H17F3N4O2S
- Molecular Weight:410.41
IUPAC Name: N-(3-hydroxypropyl)-5-methyl-1-(4-(3-(trifluoromethyl)phenyl)thiazol-2-yl)-1H-pyrazole-4-carboxamide
InChIKey: HOFGTYCLOKDAES-UHFFFAOYSA-N
SMILES: CC1=C(C(NCCCO)=O)C=NN1C2=NC(C3=CC(C(F)(F)F)=CC=C3)=CS2
Biological Activity: RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion[1].
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RWJ 50271 | 99.23% | RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion. | ||||||||||||||||||||
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RWJ 50271 (Standard) | ≥98% | RWJ 50271 (Standard) is the analytical standard of RWJ 50271 (HY-110086). This product is intended for research and analytical applications. RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion. | ||||||||||||||||||||
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