1627600-90-1
Chemical Structure
Antitumor agent-63
- CAS No.: 1627600-90-1
- Formula:C38H46N4O18
- Molecular Weight:846.79
IUPAC Name: (S)-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl (2-(2-(((2S,3S,4S,5S,6S)-3-(((2R,3S,4S,5R,6R)-4-(carbamoyloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetra
InChIKey: YFRBFEVHTILPOU-MLGQGFJNSA-N
SMILES: O[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)OC(N)=O)[C@H]1O[C@@H]([C@H]([C@@H]([C@@H](O2)CO)O)O)[C@H]2OCCOCCNC(O[C@]3(C4=C(COC3=O)C(N5C(C6=NC7=CC=CC=C7C=C6C5)=C4)=O)CC)=O
Biological Activity: Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition[1].
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Antitumor agent-63 | Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition. | |||||||||||||||||||||
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