162929-64-8
Chemical Structure
C-telopeptide
- CAS No.: 162929-64-8
- Formula:C34H56N14O13
- Molecular Weight:868.89
IUPAC Name: (2S,11S,14S,17S,20S,23S)-14-((1H-imidazol-4-yl)methyl)-23-amino-20-(4-aminobutyl)-11-(carboxymethyl)-2-(3-guanidinopropyl)-17-methyl-4,7,10,13,16,19,22-heptaoxo-3,6,9,12,15,18,21-heptaazahexacosanedioic acid
InChIKey: LOJFGJZQOKTUBR-XAQOOIOESA-N
SMILES: O=C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC(O)=O)C(NCC(NCC(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(O)=O)N
Biological Activity: C-telopeptide is a cross-linked peptide of type I collagen that is released during bone resorption and correlates with bone mineral density (BMD). C-telopeptide can be used in studies related to postmenopausal osteoporosis[1][2][3].
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C-telopeptide | C-telopeptide is a cross-linked peptide of type I collagen that is released during bone resorption and correlates with bone mineral density (BMD). C-telopeptide can be used in studies related to postmenopausal osteoporosis. | |||||||||||||||||||||
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References
- [1]. Shieh A, et al. Changes in Collagen Type I C-Telopeptide and Procollagen Type I N-Terminal Propeptide During the Menopause Transition. J Clin Endocrinol Metab. 2024 May 17;109(6):1580-1589.
- [2]. Srivastava AK, et al. Development and application of a serum C-telopeptide and osteocalcin assay to measure bone turnover in an ovariectomized rat model. Calcif Tissue Int. 2000 Jun;66(6):435-42.
- [3]. Yamaga A, et al. Changes in urinary excretions of C-telopeptide and cross-linked N-telopeptide of type I collagen during pregnancy and puerperium. Endocrine journal. 1997 Oct;44(5):733-8.
