163046-73-9
Chemical Structure
Cimicifugoside H-1
Synonym(s): Cimicidanol-3-O-β-d-xyloside
- CAS No.: 163046-73-9
- Formula:C35H52O9
- Molecular Weight:616.78
IUPAC Name: (1S,2aR,3R,5aR,7aR,9S,11aR,12aS)-3-((R)-4-((R)-3,3-dimethyloxiran-2-yl)-4-oxobutan-2-yl)-1-hydroxy-2a,5a,8,8-tetramethyl-9-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-1,2,2a,3,5,5a,7,7a,8,9,10,11-dodecahydro-4H,12H-cyclopenta[a]cycloprop
InChIKey: PYBFXJMIKJNNAJ-GLWILYKISA-N
SMILES: O[C@@H]1[C@]23[C@@]4([C@@](C(C)([C@H](CC4)O[C@H]5[C@@H]([C@H]([C@@H](CO5)O)O)O)C)([H])CC=C3[C@]6([C@](C1)([C@@](C(C6)=O)([H])[C@H](C)CC([C@H]7C(C)(O7)C)=O)C)C)C2
Biological Activity: Cimicifugoside H-1, a cyclolanostanol xyloside, is a major constituent of C. foetida L. extract. Cimicifugoside H-1 inhibits bone resorption and ovariectomy-induced bone loss[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cimicifugoside H-1 | 99.83% | Cimicifugoside H-1, a cyclolanostanol xyloside, is a major constituent of C. foetida L. extract. Cimicifugoside H-1 inhibits bone resorption and ovariectomy-induced bone loss. | ||||||||||||||||||||
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References
- [1]. Koeda M, et, al. Studies on the Chinese crude drug "shoma." IX. Three novel cyclolanostanol xylosides, cimicifugosides H-1, H-2 and H-5, from cimicifuga rhizome. Chem Pharm Bull (Tokyo). 1995 May;43(5):771-6. [Content Brief]
- [2]. Gai YY, et, al. Pharmacokinetics and bioavailability of cimicifugosides after oral administration of Cimicifuga foetida L. extract to rats. J Ethnopharmacol. 2012 Aug 30;143(1):249-55. [Content Brief]
- [3]. Li JX, et, al. Triterpenoids from Cimicifugae rhizoma, a novel class of inhibitors on bone resorption and ovariectomy-induced bone loss. Maturitas. 2007 Sep 20;58(1):59-69. [Content Brief]
