163105-64-4
Chemical Structure
SDH-IN-43
- CAS No.: 163105-64-4
- Formula:C14H10ClN
- Molecular Weight:227.69
IUPAC Name: 5-(4-chlorophenyl)-1H-indole
InChIKey: WRCFPBZUXYWGPK-UHFFFAOYSA-N
SMILES: ClC1=CC=C(C2=CC=C3NC=CC3=C2)C=C1
Biological Activity: SDH-IN-43 (Compound i-19) is a succinate dehydrogenase (SDH) inhibitor. SDH-IN-43 shows potent inhibitory activity against caenorhabditis elegans wirh an IC50 of 6.67 μM. SDH-IN-43 can significantly reduce caenorhabditis elegans reproductive ability and movement ability, and is also effective against drug-resistant strains of Levamisole (HY-A0106), Benzimidazole (HY-Y1825), and Ivermectin (HY-15310). SDH-IN-43 can be used for the research of parasite infection[1].
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SDH-IN-43 | SDH-IN-43 (Compound i-19) is a succinate dehydrogenase (SDH) inhibitor. SDH-IN-43 shows potent inhibitory activity against caenorhabditis elegans wirh an IC50 of 6.67 μM. SDH-IN-43 can significantly reduce caenorhabditis elegans reproductive ability and movement ability, and is also effective against drug-resistant strains of Levamisole (HY-A0106), Benzimidazole (HY-Y1825), and Ivermectin (HY-15310). SDH-IN-43 can be used for the research of parasite infection. | |||||||||||||||||||||
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