1632250-50-0
1632250-50-0
Chemical Structure
PF-06446846 hydrochloride
- CAS No.: 1632250-50-0
- Formula:C22H21Cl2N7O
- Molecular Weight:470.35
IUPAC Name: (R)-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)-N-(3-chloropyridin-2-yl)-N-(piperidin-3-yl)benzamide hydrochloride
InChIKey: AQSJYIVIWBIHOU-UNTBIKODSA-N
SMILES: O=C(N(C1=NC=CC=C1Cl)[C@H]2CNCCC2)C3=CC=C(N4N=NC5=CC=CN=C54)C=C3.[H]Cl
Biological Activity: PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9 (PCSK9). PF-06446846 hydrochloride inhibits PCSK9 by inducing the ribosome to stall around codon 34[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-06446846 hydrochloride | 99.44% | PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9 (PCSK9). PF-06446846 hydrochloride inhibits PCSK9 by inducing the ribosome to stall around codon 34. | ||||||||||||||||||||
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