1637373-70-6
1637373-70-6
Chemical Structure
LPE-1
- CAS No.: 1637373-70-6
- Formula:C13H10N6S3
- Molecular Weight:346.45
IUPAC Name: 2-(5-cyano-2-(prop-2-yn-1-ylthio)-6-(thiophen-2-yl)pyrimidin-4-yl)hydrazine-1-carbothioamide
InChIKey: JXKWZYDYSCQZPS-UHFFFAOYSA-N
SMILES: N#CC=1C(=NC(=NC1C=2SC=CC2)SCC#C)NNC(=S)N
Biological Activity: LPE-1 is a lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 of 0.65 μM. LPE-1 inhibits the proliferation of gastric cancer, liver cancer and prostate cancer cells, and shows no activity against a subset of gastric cancer cells. LPE-1 is applicable for the research of gastric cancer, liver cancer and prostate cancer[1].
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LPE-1 | LPE-1 is a lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 of 0.65 μM. LPE-1 inhibits the proliferation of gastric cancer, liver cancer and prostate cancer cells, and shows no activity against a subset of gastric cancer cells. LPE-1 is applicable for the research of gastric cancer, liver cancer and prostate cancer. | |||||||||||||||||||||
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