1638956-72-5
1638956-72-5
Chemical Structure
Antileishmanial agent-14
- CAS No.: 1638956-72-5
- Formula:C23H26ClNO5
- Molecular Weight:431.91
IUPAC Name: (Z)-2-(2,5-dimethoxybenzylidene)-6-(2-(pyrrolidin-1-yl)ethoxy)benzofuran-3(2H)-one hydrochloride
InChIKey: UGJKJCCMAUWUTO-YDHFHHHVSA-N
SMILES: O=C1C2=CC=C(OCCN3CCCC3)C=C2O/C1=C\C4=C(C=CC(OC)=C4)OC.Cl
Biological Activity: Antileishmanial agent-14 is a sulfuretin analog with potential activity against the parasite Leishmania donovani promastigotes (IC50=4.1 μM). Antileishmanial agent-14 also inhibits infection by L. donovani amastigotes (IC50=11.1 μM)[1].
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Antileishmanial agent-14 | Antileishmanial agent-14 is a sulfuretin analog with potential activity against the parasite Leishmania donovani promastigotes (IC50=4.1 μM). Antileishmanial agent-14 also inhibits infection by L. donovani amastigotes (IC50=11.1 μM). | |||||||||||||||||||||
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