1639220-17-9
1639220-17-9
Chemical Structure
Sigma-1 receptor antagonist 3
- CAS No.: 1639220-17-9
- Formula:C19H23ClFN3O
- Molecular Weight:363.86
IUPAC Name: 5-chloro-2-(4-fluorophenyl)-4-methyl-6-(3-(piperidin-1-yl)propoxy)pyrimidine
InChIKey: OAIHSWLLDNASTO-UHFFFAOYSA-N
SMILES: CC1=NC(C2=CC=C(F)C=C2)=NC(OCCCN3CCCCC3)=C1Cl
Biological Activity: Sigma-1 receptor antagonist 3 (compound135) is a potent and selective Sigma-1 (σ1) receptor antagonist with a Ki of 1.14 nM. Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG) with an IC50 of 1.54 μM. Sigma-1 receptor antagonist 3 has the potential for the neuropathic pain[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sigma-1 receptor antagonist 3 | 99.47% | Sigma-1 receptor antagonist 3 (compound135) is a potent and selective Sigma-1 (σ1) receptor antagonist with a Ki of 1.14 nM. Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG) with an IC50 of 1.54 μM. Sigma-1 receptor antagonist 3 has the potential for the neuropathic pain. | ||||||||||||||||||||
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