1639965-26-6
1639965-26-6
Chemical Structure
MIND4
- CAS No.: 1639965-26-6
- Formula:C24H17N5O3S
- Molecular Weight:455.49
IUPAC Name: 5-nitro-8-((5-(phenoxymethyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)quinoline
InChIKey: RVYWJVIYWKCDEE-UHFFFAOYSA-N
SMILES: O=[N+]([O-])C1=C2C=CC=NC2=C(C=C1)SC3=NN=C(N3C4=CC=CC=C4)COC5=CC=CC=C5
Biological Activity: MIND4 is a neuroprotective thiozoline compound that inhibits the deacetylase SIRT2. MIND4 is also an inducer and activator of the nuclear factor NRF2. MIND4 can induce NRF2 activation in neurons and non-neuronal cells and reduce the production of reactive oxygen and nitrogen intermediates[1].
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MIND4 | MIND4 is a neuroprotective thiozoline compound that inhibits the deacetylase SIRT2. MIND4 is also an inducer and activator of the nuclear factor NRF2. MIND4 can induce NRF2 activation in neurons and non-neuronal cells and reduce the production of reactive oxygen and nitrogen intermediates. | |||||||||||||||||||||
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