1640282-44-5

(R)-Zunsemetinib Chemical Structure
1640282-44-5

Chemical Structure

(R)-Zunsemetinib

Synonym(s): (R)-ATI-450; (R)-CDD-450

  • CAS No.: 1640282-44-5
  • Formula:C25H22ClF2N5O3
  • Molecular Weight:513.92

IUPAC Name: 3-chloro-4-((3,5-difluoropyridin-2-yl)methoxy)-2'-(2-(2-hydroxypropan-2-yl)pyrimidin-4-yl)-5',6-dimethyl-2H-[1,4'-bipyridin]-2-one

InChIKey: FQPQMJULRZINPV-UHFFFAOYSA-N

SMILES: FC1=CC(F)=CN=C1COC2=C(Cl)C(N(C3=CC(C4=NC(C(C)(C)O)=NC=C4)=NC=C3C)C(C)=C2)=O

Biological Activity: (R)-Zunsemetinib is the isomer of Zunsemetinib (HY-139553), and can be used as an experimental control. Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases[1].

Cat. No. Product Name Purity Description Pricing
HY-139553A
(R)-Zunsemetinib 97.57% (R)-Zunsemetinib is the isomer of Zunsemetinib (HY-139553), and can be used as an experimental control. Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References