164150-85-0
164150-85-0
Chemical Structure
Fandofloxacin hydrochloride
Synonym(s): DW-116 hydrochloride
- CAS No.: 164150-85-0
- Formula:C20H19ClF2N4O3
- Molecular Weight:436.84
IUPAC Name: 6-fluoro-1-(5-fluoropyridin-2-yl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
InChIKey: UPCHGBDAUCFDMW-UHFFFAOYSA-N
SMILES: O=C(C1=CN(C2=NC=C(F)C=C2)C3=C(C=C(F)C(N4CCN(C)CC4)=C3)C1=O)O.[H]Cl
Biological Activity: Fandofloxacin (DW-116) hydrochloride is an orally active quinolone antibiotic. Fandofloxacin hydrochloride is embryotoxic and teratogenic. Fandofloxacin hydrochloride can be used for the research of bacterial infection[1][2].
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Fandofloxacin hydrochloride | Fandofloxacin (DW-116) hydrochloride is an orally active quinolone antibiotic. Fandofloxacin hydrochloride is embryotoxic and teratogenic. Fandofloxacin hydrochloride can be used for the research of bacterial infection. | |||||||||||||||||||||
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References
- [1]. Yu IL, et al. Pharmacokinetics of 1-(5-fluoro-2-pyridyl)-6-fluoro-7-(4-methyl-1- piperazinyl)-1,4-dihydro-4-oxoquinolone-3-carboxylic acid hydrochloride (DW-116), a new quinolone antibiotic in rats. J Pharm Sci. 1997 May;86(5):550-3. [Content Brief]
- [2]. Kim JC, et al. Developmental toxicity evaluation of the new fluoroquinolone antibacterial DW-116 in rats. Teratog Carcinog Mutagen. 2003;Suppl 1:123-36. [Content Brief]
