1642826-40-1
Chemical Structure
BIHC
- CAS No.: 1642826-40-1
- Formula:C26H21ClN2O6
- Molecular Weight:492.91
IUPAC Name: 3,3'-((2-butyl-4-chloro-1H-imidazol-5-yl)methylene)bis(4-hydroxy-2H-chromen-2-one)
InChIKey: YDLKVAMYKVCOFK-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C(O)=C1C(C3=C(O)C4=C(C=CC=C4)OC3=O)C5=C(Cl)N=C(CCCC)N5)C=CC=C2
Biological Activity: BIHC is a TNF blocker with anti-inflammatory activity. BIHC can significantly inhibit the proliferation of hepatocellular carcinoma (HCC) cells and exhibits potent cytotoxicity against the HepG2 cell line, capable of inducing cell apoptosis , while demonstrating relatively low toxicity towards normal hepatocytes. Additionally, BIHC can be used for research on inflammatory bowel disease (IBD)[1].
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BIHC | ≥98.0% | BIHC is a TNF blocker with anti-inflammatory activity. BIHC can significantly inhibit the proliferation of hepatocellular carcinoma (HCC) cells and exhibits potent cytotoxicity against the HepG2 cell line, capable of inducing cell apoptosis , while demonstrating relatively low toxicity towards normal hepatocytes. Additionally, BIHC can be used for research on inflammatory bowel disease (IBD). | ||||||||||||||||||||
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