164365-16-6
164365-16-6
Chemical Structure
N-Desmethyl Tamoxifen-d5
- CAS No.: 164365-16-6
- Formula:C25H22D5NO
- Molecular Weight:362.52
IUPAC Name: (Z)-2-(4-(1,2-diphenylbut-1-en-1-yl-3,3,4,4,4-d5)phenoxy)-N-methylethan-1-amine
InChIKey: NYDCDZSEEAUOHN-JZSWEIPSSA-N
SMILES: [2H]C([2H])([2H])C([2H])([2H])/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(C=C3)OCCNC
Biological Activity: N-Desmethyl Tamoxifen-d5 is the deuterium labeled N-Desmethyl Tamoxifen[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Desmethyl Tamoxifen-d5 | N-Desmethyl Tamoxifen-d5 is the deuterium labeled N-Desmethyl Tamoxifen. | |||||||||||||||||||||
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N-Desmethyltamoxifen | 99.59% | N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation. | ||||||||||||||||||||
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