165393-06-6
165393-06-6
Chemical Structure
Urolithin C
- CAS No.: 165393-06-6
- Formula:C13H8O5
- Molecular Weight:244.20
IUPAC Name: 3,8,9-trihydroxy-6H-benzo[c]chromen-6-one
InChIKey: HHXMEXZVPJFAIJ-UHFFFAOYSA-N
SMILES: O=C1C2=CC(O)=C(O)C=C2C3=CC=C(O)C=C3O1
Biological Activity: Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation[1][2].
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Urolithin C | 98.00% | Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation. | ||||||||||||||||||||
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Urolithin C (Standard) | ≥98% | Urolithin C (Standard) is the analytical standard of Urolithin C. This product is intended for research and analytical applications. Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation. | ||||||||||||||||||||
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References
- [1]. Slimane Toubal, et al. Urolithin C Increases Glucose-Induced ERK Activation Which Contributes to Insulin Secretion. Fundam Clin Pharmacol. 2020 Feb 21. [Content Brief]
- [2]. Peipei Yin, et al. Urolithin C, a gut metabolite of ellagic acid, induces apoptosis in PC12 cells through a mitochondria-mediated pathway. RSC Advances. Issue 28, 2017.
