1654725-02-6
1654725-02-6
Chemical Structure
GLPG1837
Synonym(s): ABBV-974
- CAS No.: 1654725-02-6
- Formula:C16H20N4O3S
- Molecular Weight:348.42
IUPAC Name: N-(3-carbamoyl-5,5,7,7-tetramethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-3-carboxamide
InChIKey: GHTGYZMBQPXTCQ-UHFFFAOYSA-N
SMILES: O=C(C1=NNC=C1)NC(S2)=C(C(N)=O)C3=C2C(C)(C)OC(C)(C)C3
Biological Activity: GLPG1837 is a potent and reversible CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GLPG1837 | 99.87% | GLPG1837 is a potent and reversible CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively. | ||||||||||||||||||||
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GLPG1837 (Standard) | ≥98% | GLPG1837 (Standard) is the analytical standard of GLPG1837 (HY-111099). This product is intended for research and analytical applications. GLPG1837 is a potent and reversible CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively. | ||||||||||||||||||||
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