1672691-50-7
1672691-50-7
Chemical Structure
JZP-MA-11
- CAS No.: 1672691-50-7
- Formula:C15H17FN4O2S
- Molecular Weight:336.38
IUPAC Name: 3-isopropyl-1-methylpiperazine dihydrochloride
InChIKey: NLWSYKNCVGFXOV-UHFFFAOYSA-N
SMILES: FC1=CC=C(C=C1)N(C)C(OC2=NSN=C2N3CCCCC3)=O
Biological Activity: JZP-MA-11 is a brain-penetrant positron emission tomography (PET) ligand targeting the brain endocannabinoid α/β-hydrolase domain 6 (ABHD6) enzyme. JZP-MA-11 selectively inhibits ABHD6 with an IC50 value of 126 nM. [18F]JZP-MA-11 has the potential for preclinical evaluation targeting the brain ABHD6 in mice and nonhuman primate (NHP)[1].
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JZP-MA-11 | 99.26% | JZP-MA-11 is a brain-penetrant positron emission tomography (PET) ligand targeting the brain endocannabinoid α/β-hydrolase domain 6 (ABHD6) enzyme. JZP-MA-11 selectively inhibits ABHD6 with an IC50 value of 126 nM. [18F]JZP-MA-11 has the potential for preclinical evaluation targeting the brain ABHD6 in mice and nonhuman primate (NHP). | ||||||||||||||||||||
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