1675203-24-3
1675203-24-3
Chemical Structure
BMS-142
- CAS No.: 1675203-24-3
- Formula:C25H26N2O4
- Molecular Weight:418.48
IUPAC Name: 3-((4-(((2-hydroxyethyl)amino)methyl)-3,5-dimethoxyphenoxy)methyl)-[1,1'-biphenyl]-2-carbonitrile
InChIKey: CRXMIYGHZKOKII-UHFFFAOYSA-N
SMILES: N#CC1=C(COC2=CC(OC)=C(CNCCO)C(OC)=C2)C=CC=C1C3=CC=CC=C3
Biological Activity: BMS-142 is a PDL1 inhibitor (IC50 = 96.7 nM) (kd = 13.2 nM). BMS-142 can reduce the survival rate of acute T-lymphoblastic leukemia cells and ovarian cancer cells. BMS-142 can be used in research on cancers such as acute T-lymphoblastic leukemia and ovarian cancer[1].
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BMS-142 | BMS-142 is a PDL1 inhibitor (IC50 = 96.7 nM) (kd = 13.2 nM). BMS-142 can reduce the survival rate of acute T-lymphoblastic leukemia cells and ovarian cancer cells. BMS-142 can be used in research on cancers such as acute T-lymphoblastic leukemia and ovarian cancer. | |||||||||||||||||||||
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