1680228-76-5
1680228-76-5
Chemical Structure
FKBP51F67V-selective antagonist Ligand2
- CAS No.: 1680228-76-5
- Formula:C43H56N2O10
- Molecular Weight:760.91
InChIKey: ZTMQGQWEOCFOGE-QGBCWPEESA-N
SMILES: O=C(N1[C@@H](CCCC1)C(O[C@@H](C2=CC(OCCN3CCOCC3)=CC=C2)CCC4=CC(OC)=C(C=C4)OC)=O)[C@H](C5=CC(OC)=C(C(OC)=C5)OC)CC=C
Biological Activity: FKBP51F67V-selective antagonist Ligand2 (example 3-3) is a potent FKBP51 F67V-selective antagonist ligand. FKBP51F67V-selective antagonist Ligand2 reverses the anxiogenic phenotype induced by overexpression of FKBP51 F67V in the amygdala. FKBP51F67V-selective antagonist Ligand2 binds to FKBP51 F67V, but not to wild-type FKBP51 or FKBP52[1].
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FKBP51F67V-selective antagonist Ligand2 | FKBP51F67V-selective antagonist Ligand2 (example 3-3) is a potent FKBP51 F67V-selective antagonist ligand. FKBP51F67V-selective antagonist Ligand2 reverses the anxiogenic phenotype induced by overexpression of FKBP51 F67V in the amygdala. FKBP51F67V-selective antagonist Ligand2 binds to FKBP51 F67V, but not to wild-type FKBP51 or FKBP52. | |||||||||||||||||||||
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