168146-21-2
168146-21-2
Chemical Structure
Evofolin A
- CAS No.: 168146-21-2
- Formula:C10H12O4
- Molecular Weight:196.20
InChIKey: XADGCRVOLDLTQY-LURJTMIESA-N
SMILES: C[C@H](O)C(C1=CC(OC)=C(C=C1)O)=O
Biological Activity: Evofolin A is a conjugated benzophenone derivative and monocyclic polyketide that exists in the heartwood of Phellodendron chinense var. glabriusculum, the herb Sida acuta, and the filamentous fungus Aspergillus oryzae. Evofolin A acts as an inducer of quinone reductase activity in cultured hepatoma cells[1][2].
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Evofolin A | Evofolin A is a conjugated benzophenone derivative and monocyclic polyketide that exists in the heartwood of Phellodendron chinense var. glabriusculum, the herb Sida acuta, and the filamentous fungus Aspergillus oryzae. Evofolin A acts as an inducer of quinone reductase activity in cultured hepatoma cells. | |||||||||||||||||||||
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References
- [1]. Wu T S, et al. The heartwood constituents of Tetradium glabrifolium[J]. Phytochemistry, 1995, 40(1): 121-124.
- [2]. Kan E, et al. Discovery of the 2,4'-Dihydroxy-3'-methoxypropiophenone Biosynthesis Genes in Aspergillus oryzae. Chembiochem : a European journal of chemical biology. 2021 Jan 05;22(1):203-211. [Content Brief]
