1685280-21-0
1685280-21-0
Chemical Structure
mTOR inhibitor-23
- CAS No.: 1685280-21-0
- Formula:C15H8Br3NO3
- Molecular Weight:489.94
IUPAC Name: 6,8-dibromo-2-(4-bromophenyl)-3-nitro-2H-chromene
InChIKey: CYEGQBKPPSAVKF-UHFFFAOYSA-N
SMILES: BrC(C=C1)=CC=C1C2OC3=C(Br)C=C(Br)C=C3C=C2[N+]([O-])=O
Biological Activity: mTOR inhibitor-23 (compound DHM25) is a selective, competitive, irreversible and covalent inhibitor of mTOR. mTOR inhibitor-23 has the mechanism of inhibition occurs mainly through its capacity to covalently interact with a nucleophilic amino acid inside the ATP pocket. mTOR inhibitor-23 exerts potent antitumor activity against triple-negative breast tumor cell lines[1].
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mTOR inhibitor-23 | mTOR inhibitor-23 (compound DHM25) is a selective, competitive, irreversible and covalent inhibitor of mTOR. mTOR inhibitor-23 has the mechanism of inhibition occurs mainly through its capacity to covalently interact with a nucleophilic amino acid inside the ATP pocket. mTOR inhibitor-23 exerts potent antitumor activity against triple-negative breast tumor cell lines. | |||||||||||||||||||||
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