169136-33-8
169136-33-8
Chemical Structure
Necrostatin-21
- CAS No.: 169136-33-8
- Formula:C13H11N3
- Molecular Weight:209.25
IUPAC Name: 2,4,5,10-tetrahydropyrazolo[3,4-a]carbazole
InChIKey: WQSHEPAFFTVLAP-UHFFFAOYSA-N
SMILES: C1=CC=C2C(=C1)C3=C(C4=NNC=C4CC3)N2
Biological Activity: Necrostatin-21 (Compound Nec-21) is a necroptosis inhibitor with an EC50 of 0.5 μM. Necrostatin-21 has a dual inhibitory effect on the RIP1 and JNK3 kinases. Necrostatin-21 can be used for the researches of infection, cardiovascular and neurological disease, such as Alzheimer disease [1].
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Necrostatin-21 | Necrostatin-21 (Compound Nec-21) is a necroptosis inhibitor with an EC50 of 0.5 μM. Necrostatin-21 has a dual inhibitory effect on the RIP1 and JNK3 kinases. Necrostatin-21 can be used for the researches of infection, cardiovascular and neurological disease, such as Alzheimer disease . | |||||||||||||||||||||
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