169188-19-6
169188-19-6
Chemical Structure
L-692429 hydrochloride
Synonym(s): MK-0751 hydrochloride
- CAS No.: 169188-19-6
- Formula:C29H32ClN7O2
- Molecular Weight:546.06
InChIKey: WZCMWJMQSXRZBP-GJFSDDNBSA-N
SMILES: CC(C)(N)CC(N[C@H]1C(N(CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2)C5=CC=CC=C5CC1)=O)=O.Cl
Biological Activity: L-692429 (MK-0751) hydrochloride is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist. L-692429 hydrochloride binds to G protein-coupled receptor with a Ki of 63 nM[1][2].
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L-692429 hydrochloride | L-692429 (MK-0751) hydrochloride is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist. L-692429 hydrochloride binds to G protein-coupled receptor with a Ki of 63 nM. | |||||||||||||||||||||
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References
- [1]. Cheng K, et al. Inhibition of L-692,429-stimulated rat growth hormone release by a weak substance P antagonist: L-756,867. J Endocrinol. 1997 Jan;152(1):155-8. [Content Brief]
- [2]. Holst B, et al. Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling. Mol Endocrinol. 2005 Sep;19(9):2400-11. [Content Brief]
