16948-04-2
16948-04-2
Chemical Structure
Boc-Lys(Z)-OH (DCHA)
- CAS No.: 16948-04-2
- Formula:C31H51N3O6
- Molecular Weight:561.75
IUPAC Name: dicyclohexylamine N6-((benzyloxy)carbonyl)-N2-(tert-butoxycarbonyl)-L-lysinate
InChIKey: BQERJWRZLXZNIO-RSAXXLAASA-N
SMILES: O=C(O)[C@@H](NC(OC(C)(C)C)=O)CCCCNC(OCC1=CC=CC=C1)=O.C2(NC3CCCCC3)CCCCC2
Biological Activity: Boc-Lys(Z)-OH (DCHA) is a involves in synthesis thymosin β4, βg and β6 fragments, and increases E-rosette forming capacity in Lupus Nephritis model. Boc-Lys(Z)-OH (DCHA) involves in synthesis Boc-Lyz-OCH3 and acts as a reagent of peptidyl thrombin inhibitors production[1][2][3].
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Boc-Lys(Z)-OH (DCHA) | Boc-Lys(Z)-OH (DCHA) is a involves in synthesis thymosin β4, βg and β6 fragments, and increases E-rosette forming capacity in Lupus Nephritis model. Boc-Lys(Z)-OH (DCHA) involves in synthesis Boc-Lyz-OCH3 and acts as a reagent of peptidyl thrombin inhibitors production. | |||||||||||||||||||||
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References
- [1]. Abiko, et al. Synthesis of six common amino acid sequence fragments of thymosins beta 4, beta 8 and beta 9 and determination of their effects on the low E-rosette forming cells of lupus nephritis patients. Chemical & pharmaceutical bulletin, 1984.
- [2]. Cal PM, et al. Iminoboronates: a new strategy for reversible protein modification. J Am Chem Soc. 2012 Jun 20;134(24):10299-305. [Content Brief]
- [3]. Van Boeckel, et al. Preparation of peptidyl thrombin inhibitors: World Intellectual Property Organization, WO9807308. 1998-02-26.
