169543-49-1
Chemical Structure
Icrocaptide
Synonym(s): ITF1697
- CAS No.: 169543-49-1
- Formula:C21H40N8O5
- Molecular Weight:484.59
IUPAC Name: N2-ethyl-N2-glycyl-L-lysyl-L-prolyl-L-arginine
InChIKey: LPKPGXJXCZNDJO-JYJNAYRXSA-N
SMILES: NCC(N(CC)[C@@H](CCCCN)C(N1[C@@H](CCC1)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O
Biological Activity: Icrocaptide (ITF1697) is a stable Lys-Pro-containing peptide that inhibits the intracellular Ca2+-dependent fusion of Weibel-Palade bodies with the plasma membrane. Icrocaptide exerts its activity at the early stages of endothelial activation and inhibits P-selectin and von Willebrand factor secretion. Icrocaptide can be used for the study of a variety of microvascular disorders[1].
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Icrocaptide | Icrocaptide (ITF1697) is a stable Lys-Pro-containing peptide that inhibits the intracellular Ca2+-dependent fusion of Weibel-Palade bodies with the plasma membrane. Icrocaptide exerts its activity at the early stages of endothelial activation and inhibits P-selectin and von Willebrand factor secretion. Icrocaptide can be used for the study of a variety of microvascular disorders. | |||||||||||||||||||||
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