170149-76-5
170149-76-5
Chemical Structure
ReN-1869 hydrochloride
Synonym(s): NNC-05-1869 hydrochloride
- CAS No.: 170149-76-5
- Formula:C24H28ClNO2
- Molecular Weight:397.94
IUPAC Name: (R)-1-(3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)propyl)piperidine-3-carboxylic acid hydrochloride
InChIKey: OJCOPCYFLFDPTD-VEIFNGETSA-N
SMILES: O=C([C@H]1CN(CC/C=C2C3=CC=CC=C3CCC4=CC=CC=C\24)CCC1)O.[H]Cl
Biological Activity: ReN 1869 hydrochloride is a novel, selective histamine H1 receptor antagonist, which demonstrates affinity to the histamine H1 receptor (guinea pig brain) with Ki of 0.19±0.04 μM and the non-selective σ site (guinea pig brain) with Ki of 0.45 μM.
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ReN-1869 hydrochloride | ReN 1869 hydrochloride is a novel, selective histamine H1 receptor antagonist, which demonstrates affinity to the histamine H1 receptor (guinea pig brain) with Ki of 0.19±0.04 μM and the non-selective σ site (guinea pig brain) with Ki of 0.45 μM. | |||||||||||||||||||||
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