170368-04-4
Chemical Structure
Anisperimus
Synonym(s): LF-150195
- CAS No.: 170368-04-4
- Formula:C18H39N7O3
- Molecular Weight:401.55
IUPAC Name: (R)-2-((6-guanidinohexyl)amino)-2-oxoethyl (4-((3-aminobutyl)amino)butyl)carbamate
InChIKey: PZDPVSFZTKORSP-OAHLLOKOSA-N
SMILES: C[C@@H](N)CCNCCCCNC(OCC(NCCCCCCNC(N)=N)=O)=O
Biological Activity: Anisperimus (LF-150195) is an immunosuppressant with the activity of enhancing activation-induced T cell death. Anisperimus enhances the sensitivity of T cells to anti-CD95 antibodies and other inducers by promoting the activation of caspase-8 and caspase-10 at the level of the death-inducing signaling complex (DISC). Anisperimus also promotes the development of Foxp3-expressing regulatory CD4 T cells, thereby preventing central nervous system autoimmunity[1].
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Anisperimus | Anisperimus (LF-150195) is an immunosuppressant with the activity of enhancing activation-induced T cell death. Anisperimus enhances the sensitivity of T cells to anti-CD95 antibodies and other inducers by promoting the activation of caspase-8 and caspase-10 at the level of the death-inducing signaling complex (DISC). Anisperimus also promotes the development of Foxp3-expressing regulatory CD4 T cells, thereby preventing central nervous system autoimmunity. | |||||||||||||||||||||
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