171277-06-8
Chemical Structure
JTH-601 free base
- CAS No.: 171277-06-8
- Formula:C24H35NO4
- Molecular Weight:401.54
IUPAC Name: 3-(((2-(4-hydroxy-2-isopropyl-5-methylphenoxy)ethyl)(methyl)amino)methyl)-4-methoxy-2,5,6-trimethylphenol
InChIKey: VXLRYJNESHCVDX-UHFFFAOYSA-N
SMILES: OC1=C(C)C=C(OCCN(CC2=C(C(C)=C(C)C(O)=C2C)OC)C)C(C(C)C)=C1
Biological Activity: JTH-601 Free base is a novel alpha1-adrenoceptor antagonist that exhibits potent activity in inhibiting phenylephrine-induced contractions in lower urinary tract tissues. JTH-601 Free base competitively antagonizes alpha1-adrenoceptor-mediated contractile responses, demonstrating greater potency than prazosin or tamsulosin. JTH-601 Free base is anticipated to be effective in treating urinary outlet obstruction associated with benign prostatic hyperplasia.
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JTH-601 free base | JTH-601 Free base is a novel alpha1-adrenoceptor antagonist that exhibits potent activity in inhibiting phenylephrine-induced contractions in lower urinary tract tissues. JTH-601 Free base competitively antagonizes alpha1-adrenoceptor-mediated contractile responses, demonstrating greater potency than prazosin or tamsulosin. JTH-601 Free base is anticipated to be effective in treating urinary outlet obstruction associated with benign prostatic hyperplasia. | |||||||||||||||||||||
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