172277-82-6
172277-82-6
Chemical Structure
J-104118
- CAS No.: 172277-82-6
- Formula:C28H26Cl2FNO5
- Molecular Weight:546.41
IUPAC Name: (S)-2-(2-(((2S,3S)-4-(3,4-dichlorophenyl)-3-(2-fluoro-[1,1'-biphenyl]-4-yl)butan-2-yl)amino)-2-oxoethyl)succinic acid
InChIKey: NBRLADMQSZWKGO-XUEUYAKLSA-N
SMILES: O=C([C@H](CC(O)=O)CC(N[C@@H](C)[C@@H](CC1=CC=C(C(Cl)=C1)Cl)C2=CC=C(C(F)=C2)C3=CC=CC=C3)=O)O
Biological Activity: J-104118 is a potent and orally active squalene synthase (SQS) inhibitor with an IC50 of 0.52 nM. J-104118 inhibits cholesterol synthesis in mice. J-104118 can be used for cholesterol-lowering research[1].
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J-104118 | J-104118 is a potent and orally active squalene synthase (SQS) inhibitor with an IC50 of 0.52 nM. J-104118 inhibits cholesterol synthesis in mice. J-104118 can be used for cholesterol-lowering research. | |||||||||||||||||||||
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