172646-43-4
Chemical Structure
5-Nitro BAPTA tetramethyl ester
- CAS No.: 172646-43-4
- Formula:C26H31N3O12
- Molecular Weight:577.54
IUPAC Name: dimethyl 2,2'-((2-(2-(2-(bis(2-methoxy-2-oxoethyl)amino)-5-nitrophenoxy)ethoxy)phenyl)azanediyl)diacetate
InChIKey: SKSQLUXELUIUKW-UHFFFAOYSA-N
SMILES: O=C(OC)CN(C1=CC=CC=C1OCCOC2=CC([N+]([O-])=O)=CC=C2N(CC(OC)=O)CC(OC)=O)CC(OC)=O
Biological Activity: 5-Nitro BAPTA tetramethyl ester is a calcium chelator. 5-Nitro BAPTA tetramethyl ester involves in the two-photon probe synthesis, and is used for real-time imaging of intracellular calcium ions, calcium waves monitoring at a depth of 100-300 μm in liver tissues for 1100-4000 s. 5-Nitro BAPTA tetramethyl ester, together with fluorescent compound 2-Me-substituted TM, can be used to form a red fluorescent probe (CaTM-2 AM)[1][2].
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5-Nitro BAPTA tetramethyl ester | 5-Nitro BAPTA tetramethyl ester is a calcium chelator. 5-Nitro BAPTA tetramethyl ester involves in the two-photon probe synthesis, and is used for real-time imaging of intracellular calcium ions, calcium waves monitoring at a depth of 100-300 μm in liver tissues for 1100-4000 s. 5-Nitro BAPTA tetramethyl ester, together with fluorescent compound 2-Me-substituted TM, can be used to form a red fluorescent probe (CaTM-2 AM). | |||||||||||||||||||||
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References
- [1]. Egawa T, et al. Red fluorescent probe for monitoring the dynamics of cytoplasmic calcium ions. Angew Chem Int Ed Engl. 2013 Apr 2;52(14):3874-7. [Content Brief]
- [2]. Cho Bong Rae, et al. Two-photon probe for real-time monitoring of intracellular calcium ions, method for preparing the probe and method for real-time monitoring of intracellular calcium ions using the probe: World Intellectual Property Organization, WO2009031734[P]. 2009-03-12.
